Description
Folic acid amp from Hevert, 20 mg in 2 ml vial
Applications
Treatment of folate deficiency in dialysis patients when oral folic acid substitution is not possible or if oral supplementation is not efficient.
Composition
20 mg folic acid in 2 ml
Other ingredients:
Sodium chloride, sodium hydroxide, water for injections.
Dosage
Unless otherwise ordered individually from 1 to 3 times a week for half an inject up to 1 ampoule intramuscular or intravenously.
Contraindications
Folic acid should not be used in megaloblastic anemia due to isolated vitamin B12 deficiency. In megaloblastic anemia of unknown cause should be tested prior to treatment, whether a folic acid deficiency. Pregnancy and lactation: For doses up to 5 mg of folic acid per day are no known risks. In higher doses of folic acid should be in the pregnancy and lactation are not applied.
Side effects
In rare cases, allergic reactions, including itching, skin rash, breathing problems and shock. After high doses may increase the seizure readiness of additional therapy with antiepileptic drugs. Furthermore, in rare cases have been observed after high doses of disturbances in the gastrointestinal tract, nightmares, agitation and depression.
Interactions
Increase in convulsions in anticonvulsant therapy, particularly at high doses for treatment of poisoning with folic acid antagonists. Folic acid may not be simultaneous with, but may be given only after folic acid antagonists. Even with life-threatening megaloblastic anemia due to the risk of irreversible neurological disorders prior to treatment, the diagnosis of a possible vitamin B12 deficiency can be excluded. As a result of folic acid and vitamin B12 in the blood reticulocyte count, the administration of either vitamin may mask the lack of other vitamin.
