Glucosamine Sulfate – Glucosamine has been used for arthritis ( osteoarthritis ). Some herbal/ diet supplement products have been found to contain possibly harmful impurities/additives. Check with your pharmacist for more details about the brand you use. The FDA has not reviewed this product for safety or effectiveness. Consult your doctor or pharmacist for more details. Lidocaine Hydrochloride – A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of procaine but its duration of action is shorter than that of bupivacaine or prilocaine. Indication: For production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks. Dona 400-S Injections (Lidocaine Hydrochloride) is an anesthetic agent indicated for production of local or regional anesthesia and in the treatment of ventricular tachycardia occurring during cardiac manipulation, such as surgery or catheterization, or which may occur during acute myocardial infarction, digitalis toxicity, or other cardiac diseases. The mode of action of the antiarrhythmic effect of Dona 400-S Injections (Lidocaine Hydrochloride) appears to be similar to that of procaine, procainamide and quinidine. Ventricular excitability is depressed and the stimulation threshold of the ventricle is increased during diastole. The sinoatrial node is, however, unaffected. In contrast to the latter 3 drugs, Dona 200-S Injections (Lidocaine Hydrochloride) in therapeutic doses does not produce a significant decrease in arterial pressure or in cardiac contractile force. In larger doses, Dona 200-S Injections (Lidocaine Hydrochloride) may produce circulatory depression, but the magnitude of the change is less than that found with comparable doses of procainamide.