Fitomenadion K1 vitamin 10 mg 10×1 ml


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10×1 ml amp of fitomenadion K1 vitamin, 10 mg/ml

Vitamin K1  inj. (Phytonadione Injectable Emulsion, USP) is a yellow, sterile, nonpyrogenic aqueous dispersion available for injection by the intravenous, intramuscular and subcutaneous routes. Each milliliter contains phytonadione 10 mg, polyoxyethylated fatty acid derivative 70 mg, dextrose, hydrous 37.5 mg in water for injection; benzyl alcohol 9 mg added as preservative. May contain hydrochloric acid for pH adjustment. pH is 6.3 (5.0 to 7.0). Phytonadione is oxygen sensitive.

Consecutive congenital hypoprothrombinemia or adm. coumarin-type preparations, vitamin deficiency. K IH and obstructive jaundice, intestinal absorption disorders after treatment. Long-term oral antibiotics, sulfonamides or salicylates, warfarin poisoning, hemorrhagic disease of the newborn.

Dosage and administration:
Adults:  very slow IV, 2-10 mg / day in acute poisoning with coumarin derivatives up to 40 mg / day intramuscularly curative, 5-40 mg / day. Neonates and infants with hemorrhagic disease: prophylactic intramuscular 0.5 to 2 mg / day or oral 1-2 mg / day curative intramuscularly 1-2 mg / day.

Phytomenadione intolerance.

Hypoprothrombinemic of hepatocellular disease usually responds poorly to treatment or not.

Newborns and infants.
Adverse reactions:
Inj. rapid IV: Sweating, flushing, dyspnea, cyanosis, tachycardia, peripheral vascular collapse, or even fatal accidents, in newborns, in rare cases: hyperbilirubinemia, in patients with liver disease, inj. Repeated intramuscular – local cutaneous and subcutaneous changes.


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