Dutasteride mesotherapy is one of the very few solutions as of today that is really capable to regrow your hair.
Dutasteride is the only approved DHT-blocker substance that acts on both isomers of the 5-alpha reductase enzyme and it is effective in both genders. It has a lot higher potency than finasteride in blocking the 5-AR enzyme.
1 vial of 10 ml – about 2 ml is used per session, depending on the technique – the better the technique, less the spilling
EVALUATION OF THE EFFECT OF INJECTION OF DUTASTERIDE AS MESOTHERAPEUTIC TOOL IN TREATMENT OF ANDROGENETIC ALOPECIA IN MALES
Introduction: Androgenetic alopecia (AGA) is hereditary and androgen dependent, progressive thinning of the scalp hair that follows a defined pattern.
Aim ot the work: is to evaluate the efficacy and safety of mesotherapy using dutasteride in treatment of androgenetic alopecia in males.
Materials and Methods: Ninety male patients were randomly assigned into three groups; group A containing 30 patients who received pure
dutasteride, group B of another 30 patients who received dutasteride containing solution and group C of the remaining 30 patients who
received saline. Each group was given nine mesotherapy sessions. Assessment was done using trichogram, independent observer assessment
of photographs and patients self assessment together with evaluation of possible systemic absorption using semenogram and serum
Result: Statistical analysis of the thrichogram results, the effect on semenogram and the serum level of dihydrotestosterone.showed that
dutastride containing solution was the best.
Conclusion: Mesotherapy using dutasteride is a good option for treatment of male pattern hair loss; resulting in reduction or cessation of hair
loss and promotion of new hair growth.
Key words: methotherapy; dutastride; male; androgenetic alopecia; trichogram
Mesotherapy using dutasteride-containing preparation in treatment of female pattern hair loss: photographic, morphometric and ultrastructural evaluation
Treatment of female pattern hair loss (FPHL) is frustrating for both patients and doctors. Mesotherapy is a novel treatment for hair fall and its efficacy in FPHL has not been evaluated.
Evaluation of the efficacy and safety of mesotherapy using dutasteride-containing preparation in treatment of FPHL.
This study included 126 female patients with FPHL. They were classified into two groups; group I (86 patients) injected with dutasteride-containing preparation and group II (40 control patients) injected with saline. Patients received 12 sessions and were evaluated at the 18th week by: photographic assessment, hair pull test, hair diameter and patient self-assessment. Ultrastructural evaluation was done for three patients.
After mesotherapy with dutasteride-containing preparation, photographic improvement occurred in 62.8% of patients compared with 17.5% in control group (P < 0.05), mean number of epilated hairs was significantly decreased (P < 0.05), mean hair diameter was significantly increased (P < 0.05). Patient self-assessment showed statistically significant improvement compared with the controls (P < 0.05). There was a negative correlation between degree of improvement and duration of FPHL (P < 0.05). Side effects were minimal with no statistically significant difference between the two groups (P > 0.05). Ultrastructural examination of pretreated hairs revealed absent cuticle in one patient and focal destruction of the cuticle in the second patient, which reappeared in both after therapy.
We concluded that mesotherapy with dutasteride-containing preparation was effective, tolerable and minimally invasive treatment modality in FPHL with better response for shorter duration of the disease.