Bio-Path Announces Clinical Update to Interim Analysis of Phase 2 Prexigebersen Trial in Acute Myeloid Leukemia

March 06, 2019 08:00 ET | Source: Bio-Path Holdings, Inc. Interim Data Update from Phase 2 Study Demonstrates Meaningful Clinical Improvement with Excellent Patient Safety Profile Company Provides Clinical Development Plan with Pathways to Registration HOUSTON, March 06, 2019 (GLOBE NEWSWIRE) — Bio-Path […]

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Actovegin increases oxidative capacity in human skeletal muscle

Abstract Actovegin, a deproteinized haemodialysate of calf blood, is suggested to have ergogenic properties, but this potential effect has never been investigated in human skeletal muscle. To investigate this purported ergogenic effect, we measured the mitochondrial respiratory capacity in permeabilized […]

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Platelet Rich Fibrin in Periodontal Practice

International Journal of Dental Sciences and Research, 2017, Vol. 5, No. 5, 132-136   by Abdullah Almutairi Autologous platelet concentrates have become a rage in the field of regenerative medicine including numerous specialties like orthopedics, maxillofacial and cosmetic surgery, sports medicine […]

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Utilization of Autologous Concentrated Growth Factors (CGF) Enriched Bone Graft Matrix (Sticky Bone) and CGF-Enriched Fibrin Membrane in Implant Dentistry

Platelets are known to release several growth factors which stimulate tissue regeneration. Several techniques for platelet concentrates have been introduced in surgical field for the prevention of hemorrhage and acceleration of tissue regeneration. Platelet rich plasma (PRP) and plasma rich […]

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Modified follistatin (FS315) shows promising results to increase muscle size and fight obesity

Protein Engineering on Human Recombinant Follistatin: Enhancing Pharmacokinetic Characteristics for Therapeutic Application Chuan Shen, Andrea Iskenderian, Dianna Lundberg, Tao He, Kathleen Palmieri, Robert Crooker, Qingwei Deng, Matthew Traylor, Sheng Gu, Haojing Rong, David Ehmann, Brian Pescatore, Bettina Strack-Logue, Alla Romashko, George Baviello, John Gill, Bohong Zhang, Muthuraman Meiyappan, Clark Pan and Angela W. Norton Journal of Pharmacology and […]

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Peptide bioregulators: A new class of geroprotectors (excerpt)

Abstract This paper reviews the results of long-term studies by the authors on the clinical efficacy of peptide bioregulators (Timalin, Thymogen, Vilon, Epithalamin, Prostatilen, Cortexin, and Retinalamin) for the prevention of diseases and treatment of people of all ages. Particular […]

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Platelet-rich fibrin (PRF) treatment in periodontal disease

Abstract Platelets can play a crucial role in periodontal regeneration as they are reservoirs of growth factors and cytokines which are the key factors for regeneration of the bone and maturation of the soft tissue. Platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) are autologous platelet concentrates prepared from patient’s […]

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The Effects of Platelet-Derived Growth Factor-BB on Human Dental Pulp Stem Cells Mediated Dentin-Pulp Complex Regeneration

Abstract Dentin‐pulp complex regeneration is a promising alternative treatment for the irreversible pulpitis caused by tooth trauma or dental caries. This process mainly relies on the recruitment of endogenous or the transplanted dental pulp stem cells (DPSCs) to guide dentin‐pulp […]

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